Analytical Techniques Offered

Callan Pharma Services has all the requisite analytical equipment and expertise to analyze nanoparticle drug formulations, all common small molecule dosage forms, and protein formulations.

Gel permeation/Size exclusion Chromatography (GPC/SEC)
  • Size and poly dispersity of polymers
  • Protein aggregation

Dynamic Light Scattering (DLS)
  • Size and polydispersity of nanoparticles
Ultra-performance liquid chromatography (UPLC)
  • Assay and purity of small molecules and peptides

Additional Analytical Techniques Offered

Callan Pharma Services has relationships with 3rd party vendors to perform additional analytical techniques with no pass-through cost to clients.

Gas Chromatography-Mass Spectroscopy (GC-MS)
  • Residual solvent testing
Fourier-transform infrared spectroscopy (FT-IR)
  • Identification
  • Reaction monitoring
Microscopy
  • Particulate matter analysis

Routine Analytical Techniques Offered

Viscosity
  • Rotational viscometer
  • Viscosity is of particular importance for sub-Q delivery
Moisture
  • Karl Fisher
  • Critical parameter for lyophilized drug products
Osmolarity
  • Vapor pressure osmometer
  • Necessary for parenteral and ophthalmic routes of delivery
Turbidity
  • Drug formulation stability indicator
  • Ophthalmic solutions