Dosage Forms

Clear and sterile filtration ready solutions for small molecules and peptides

Best for: API which are freely soluble with aqueous excipients

We watch: syringeability & injectability (injectables) and clarity (topical ophthalmics)

Routes: IV, SC, IM, ID, ocular injections (e.g., intravitreal), topical ophthalmic

Dispersed drug particles in high concentrations—mostly aqueous.

Best for: Poorly water-soluble APIs when the use solubilizing excipients is not possible

We watch: sterilization methods, redispersibility, storage stability  

Routes: SC/IM (depot),  ocular injections (e.g., suprachoroidal injection), topical ophthalmics

Kinetically-stable, lipid-based vehicle for hydrophobic drugs

Best for: Hydrophobic drugs which require dose or PK tuning (retention/ release)  

We watch: sterilization, redispersibility, storage stability  

Routes: SC, IM, IV, topical ophthalmics 

(incl. lyo-enabled self-assembly)

Solid porous ‘cake’ made by removing water by sublimation—redispersed in aqueous media before administration.

Best for: Hydrophilic or hydrophobic APIs with shelf-life challenges, and candidates that benefit from nanoparticle delivery (e.g., PK tuning).

We watch: residual water/solvent, lyophilized cake morphology, reconstitution properties (e.g., time, and particle size)

Routes: IV, SC, IM, ID, ocular injections (e.g., intravitreal), topical ophthalmic