At Callan Pharma Services, our equipment and instrumentation support formulation development, analytical testing, and process development for a wide range of pharmaceutical programs. With in-house capabilities for ophthalmic, injectable, and other complex drug products, we help clients move efficiently from early feasibility through formulation optimization and analytical characterization.
Formulation Equipment
Callan specializes in complex formulation development for ophthalmic and injectable drug products. Our in-house formulation equipment supports a wide range for formulation techniques, including nanoparticle, emulsion, and lyophilized drug products.
- Millrock LD85 lyophilizer
- Microfluidics M110Y microfluidizer
- Microfluidics LM20 microfluidizer
- Misonix XL-2000 probe sonicator
- Silverson L5M-A rotor/stator homogenizer
- Fisherbrand 850 rotor/stator mixer with various heads
- Pendotech PressureMAT pressure gauge
- Cole Parmer sonicating water baths
- Various 2, 3, 4, and 5 digit balances
- Masterflex L/S peristaltic pumps
- Various 2 µL to 10 mL volumetric pipets (air displacement and positive displacement)
- Various refrigerators and freezers
- Fisher Isotemp recirculating chiller
- Harvard Apparatus syringe pump
Chromatography Systems
A reliable HPLC method is critical to formulation development as it allow for both assay and purity of the drug substance in test formulations. Size exclusion chromatography is useful for evaluating polymer excipients as well as certain aggregates in solution.
- Waters Acquity UPLC (PDA detector)
- Shimadzu LC40 HPLC (dual wavelength UV detector)
- Size Exclusion Chromatography System
- Shimadzu LC20AD pump
- Shimadzu CTO-20AC column heater/chiller
- Shimadzu SPD-20AV UV detector
- Wyatt Optilab T-rEX refractive index detector
- Wyatt TREOS light scattering detector
Analytical Instrumentation
Callan Pharma Services analytical instrumentation supports characterization of formulation profiles such as pH, osmolality, viscosity, and particle size. These tools generate the data that guides lead formulation selection, development feasibility assessments, and product stability.
- Dynamic Light Scattering – Wyatt DynaPro III plate reader
- Microscopy – Accuscope optical microscope (4-40x objectives with digital imaging)
- Karl Fisher – Mettler Toledo C20 Coulometric KF Titrator
- Osmolality – Precision Systems Osmette A freezing point depression osmometer
- Osmolality – Wescor 5500 vapor pressure osmometer
- pH – Fisher Accumet AE150 pH meter
- Viscosity – Brookfield DVNext viscometer
Partner with Callan Pharma
Callan Pharma provides its partners rapid, comprehensive and cost-effective solutions for their difficult formulation development projects.
